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A sudden outbreak of hives—red, itchy patches on the skin—combined with trouble breathing can be a sign of anaphylaxis, a severe and potentially life-threatening allergic reaction. Symptoms may begin quickly and worsen within minutes, so it’s important not to ignore them.

Warning signs include wheezing, tightness in the throat or chest, swelling of the lips or tongue, dizziness, fainting, nausea, or a rapid heartbeat. In some cases, the person may feel weak, confused, or struggle to speak normally.

Common triggers include certain foods such as peanuts or shellfish, medications, insect stings, and latex. Even people with no previous history of severe allergies can experience an unexpected reaction.

If someone develops hives along with breathing difficulties, seek emergency medical help immediately. Use an epinephrine auto-injector if one is available, and do not wait to see if symptoms improve on their own. Quick treatment can save a life.

Even when a rash appears mild, any sign of breathing problems should be treated as an emergency. Acting fast is critical because anaphylaxis can progress rapidly and become fatal without prompt medical care.

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